From 1995 onwards, Humayun Saeed associated himself with Pakistani television. First Humayun Saeed appeared as an artist in numerous television plays and drama serials. Later, Humayun Saeed started his own production, known as H.S. Production. from 'H.S. Production, Humayun Saeed has also produced long plays like 'Pehli Khahish', 'Adhuray Khawab', 'Dil wo bay mehar' and 'Undekhi'.
Recently Humayun Saeed signed a venture with the Indian director Mahesh Bhatt for his movie Jashnn which was released in early august.Humayun Saeed's Indian Film Jashnn failed so miserably that it was rejected by audiences and critics on its very opening night. Jashnn tells the story of Adhyayan Suman, an aspiring rockstar, whose sister (played by Shahana Goswami) is a mistress of a multimillionaire (Humayun Saeed).
“Newcomer Humayun Saeed is quite the surprise package. He completely overshadows Adhyayan. He has by far one of the best villains, who can steal the audience's heart,” rediif.com talled about Humayun Saeed in Jashnn.
Humayun Saeed worked in an Indian movie, Jashnn which did not do good in cinema but his acting was appreciated.